abstract aim and background: evaluation of cognition is fundamental for every comprehensive epilepsy program. we sought to conduct this study to assess memory state of patients with refractory temporal lobe epilepsy before decision for epilepsy surgery. method and materials: in a case-control study, 20 patients with right temporal lobe epilepsy and 20 patients with left temporal lobe epilepsy w...

Anxiety and depression are very common in population and occur in a wide range of clinical states and is very common in epileptic patients. Many recent epidemiological studies have found a high prevalence of depression and anxiety in epileptic patients. These studies found that epileptic patients suffered from depression and anxiety than those without epilepsy. The prevalence of depression or a...

anxiety and depression are very common in population and occur in a wide range of clinical states and is very common in epileptic patients. many recent epidemiological studies have found a high prevalence of depression and anxiety in epileptic patients. these studies found that epileptic patients suffered from depression and anxiety than those without epilepsy. the prevalence of depression or a...

We summarize some of the most frequenthly used rodent animal models of temporal lobe epileps and the impact of chemoconvulsants on them. Temporal lobe epilepsy is the most common epilepsy in humans in which seizures spread to the neighboring cortiase and hippocampal neuron loss and other neuropathological take place. Temporal lobe epilepsy and the other form of epilepsy cannot acquired in chini...

BACKGROUND Proton magnetic resonance spectroscopy (1H-MRS) is a potentially useful tool in the in vivo investigation of brain metabolites in intractable temporal lobe epilepsy (TLE). Focal N-acetylaspartate (NAA) reductions have been correlated with mesial temporal sclerosis (MTS) in surgically resected epileptogenic foci. OBJECTIVE To evaluate the abnormalities in the metabolites NAA, creati...

Background: Epilepsy is considered as one of the most important disorders in neurology. Temporal lobe epilepsy is a form of epilepsy including two main types of mesial and lateral (neocortex). Objectives: Determination and comparison of electroencephalogram (EEG) pattern in the ictal and interictal phases of mesial and lateral temporal lobe epilepsy. Materials and Methods: This cross-sectiona...

Objective: To examine the expressions of mitochondrial translation elongation factors Tu (EF-Tumt) and Ts (EF-Tsmt) in the epileptogenic zone of patients with refractory temporal lobe epilepsy. Methods: Epileptogenic zone resection specimens were obtained from 20 patients with refractory temporal lobe epilepsy. Control samples were temporal lobe cortex tissues derived from 6 non-epileptic patie...

in this research, we have computationally investigated a mechanism for antiepileptic drugs (aed) and proposed bumetanide as a possible temporal lobe epilepsy (tle) treatment. experimentally it is difficult and devastating to determine the ionic mechanisms of depolarizing currents. it is obvious that chlorine and potassium transients are challenging to isolate pharmacologically and much γ-aminob...

Functional magnetic resonance imaging has demonstrated reorganisation of memory encoding networks within the temporal lobe in temporal lobe epilepsy, but little is known of the extra-temporal networks in these patients. We investigated the temporal and extra-temporal reorganisation of memory encoding networks in refractory temporal lobe epilepsy and the neural correlates of successful subsequent